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Nature has generated sophisticated and complex molecular motors, employed for nanoscale transport at the intracellular level. As a complementary tool to nanofluidics, these motors have been envisioned for nanotechnological devices. In order to pave the way for such applications, a thorough understanding of the mechanisms governing these motors is needed. Because of the complexity of their in-vivo functions, this understanding is best acquired in-vitro, where functional parameters can independently be controlled. I will report on work in my group that studies and harnesses the transport properties of molecular motors on functionalized structures of reduced dimensionality, such as carbon nanotubes, 1 lithographically designed electrodes 2 and microwires. 31 Molecular Motor-Powered Shuttles along Multi-walled Carbon Nanotube Tracks. A. Sikora et al. Nano Lett. 14, 876-881 (2014). 2 Surface Manipulation of Microtubules Using Self-Assembled Monolayers and Electrophoresis. J. A. Noel et al., ACS Nano 3, 1938 (2009). 3 Microtubule shuttles on kinesin-coated glass micro-wire tracks. K. Kim et al. Biomed. Microdev., 16, 501-508 (2014). Functional Localization of a Kinesin/Microtubule-Based Motility System along Metallic Glass Microwires. K. Kim et al. Appl. Phys. Lett. 105, 143701 (2014).